2-Aminoquinoline (Standard)
2-Aminoquinoline (2-Quinolinamine) is a promising compound as bioavailable nNOS inhibitor but suffers from low human nNOS inhibition, low selectivity versus human eNOS, and significant binding to other CNS targets. 2-Aminoquinoline exhibits antiviral activity against the vaccinia virus. 2-Aminoquinoline has the potential for the research of antineurodegenerative agents[1][2].
Product Specifications
CAS Number
[580-22-3]
UNSPSC
12352005
Target
NO Synthase; Orthopoxvirus
Related Pathways
Anti-infection; Immunology/Inflammation
Field of Research
Infection; Neurological Disease
Smiles
NC1=NC2=CC=CC=C2C=C1
Molecular Formula
C9H8N2
Molecular Weight
144.18
References & Citations
[1]Pensa AV, et al. Hydrophilic, Potent, and Selective 7-Substituted 2-Aminoquinolines as Improved Human Neuronal Nitric Oxide Synthase Inhibitors. J Med Chem. 2017;60 (16) :7146-7165.|[2]Smee DF, et, al. A review of compounds exhibiting anti-orthopoxvirus activity in animal models. Antiviral Res. 2003 Jan;57 (1-2) :41-52.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Curated Selection
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