Maleimide (Standard)

Maleimide (Standard) is the analytical standard of Maleimide (HY-W007324) . This product is intended for research and analytical applications. Maleimide can be used for production of antibody-drug conjugate (ADC) which is used in cancer research. Maleimide also be leveraged for the preparation of fluorogenic probe, which is mainly used for the specific detection of thiol analytes[1][2].

Product Specifications

CAS Number

[541-59-3]

Target

ADC Linker; Biochemical Assay Reagents; Reference Standards

Related Pathways

Antibody-drug Conjugate/ADC Related; Others

Field of Research

Cancer

Smiles

O=C(N1)C=CC1=O

Molecular Formula

C4H3NO2

Molecular Weight

97.07

References & Citations

[1]Renault K, et, al. Covalent Modification of Biomolecules through Maleimide-Based Labeling Strategies. Bioconjug Chem. 2018 Aug 15;29 (8) :2497-2513.|[2]Zhang S, et, al. A Maleimide-functionalized Tetraphenylethene for Measuring and Imaging Unfolded Proteins in Cells. Chem Asian J. 2019 Mar 15;14 (6) :904-909.|[3]Li T, et al., A novel application of maleimide for advanced drug delivery: in vitro and in vivo evaluation of maleimide-modified pH-sensitive liposomes. Int J Nanomedicine. 2013;8:3855-66.