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1-Phenylindole

1-Phenylindole (Compound 8) is a 1-Phenylbenzimidazole analogue. 1-Phenylindole shows IC50 values of >50 μM and >50 μM for PDGFR and FGFR, respectively. 1-Phenylbenzimidazole is a selective PDGFR inhibitor[1].

Product Specifications

CAS Number

16096-33-6

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Drug Derivative; FGFR; PDGFR

Related Pathways

Others; Protein Tyrosine Kinase/RTK

Field of Research

Others

Purity

99.78

Smiles

C=1C=CC(=CC1)N2C=CC=3C=CC=CC32

Molecular Formula

C14H11N

Molecular Weight

193.25

Precautions

H302, H315, H319, H335

References & Citations

[1]Palmer BD, et al. Structure-activity relationships for 1-phenylbenzimidazoles as selective ATP site inhibitors of the platelet-derived growth factor receptor. J Med Chem. 1998 Dec 31;41 (27) :5457-65.

Shipping Conditions

Room Temperature

Storage Conditions

Store at room temperature 3 years

Scientific Category

Reference compound2

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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