1-Phenylindole
1-Phenylindole (Compound 8) is a 1-Phenylbenzimidazole analogue. 1-Phenylindole shows IC50 values of >50 μM and >50 μM for PDGFR and FGFR, respectively. 1-Phenylbenzimidazole is a selective PDGFR inhibitor[1].
Product Specifications
CAS Number
16096-33-6
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Drug Derivative; FGFR; PDGFR
Related Pathways
Others; Protein Tyrosine Kinase/RTK
Field of Research
Others
Purity
99.78
Smiles
C=1C=CC(=CC1)N2C=CC=3C=CC=CC32
Molecular Formula
C14H11N
Molecular Weight
193.25
Precautions
H302, H315, H319, H335
References & Citations
[1]Palmer BD, et al. Structure-activity relationships for 1-phenylbenzimidazoles as selective ATP site inhibitors of the platelet-derived growth factor receptor. J Med Chem. 1998 Dec 31;41 (27) :5457-65.
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Reference compound2
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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