7-Methoxy-1-tetralone
7-Methoxy-1-tetralone is a potent antitumor agent. 7-Methoxy-1-tetralone inhibits cancer cell proliferation and migration, and induces hepatocellular carcinoma cell (HCC) apoptosis. 7-Methoxy-1-tetralone decreased the protein levels of NF-κB, matrix metallopeptidase 2 (MMP2) /MMP9, and p-AKT. 7-Methoxy-1-tetralone showed antitumor activity in nude mice and had no effect on body weight and liver, spleen and organ index[1].
Product Specifications
CAS Number
6836-19-7
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H332, H335
Target
Akt; Apoptosis; c-Met/HGFR; MMP; NF-κB
Related Pathways
Apoptosis; Metabolic Enzyme/Protease; NF-κB; PI3K/Akt/mTOR; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Purity
99.93
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(CCC1)C2=C1C=CC(OC)=C2
Molecular Formula
C11H12O2
Molecular Weight
176.22
Precautions
H302, H315, H319, H332, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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