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3-Hydroxyphenylacetic acid-d5

2- (3-Hydroxyphenyl-2,4,6-d3) acetic-2,2-d2 acid is the deuterium labeled 3-Hydroxyphenylacetic acid (HY-W001083) . 3-Hydroxyphenylacetic acid is an orally active flavonoid metabolite produced by intestinal flora, with blood pressure-lowering activity. 3-Hydroxyphenylacetic acid can also inhibit ferroptosis by upregulating the expression of GPX4, thereby improving spermatogenic dysfunction in aged mice. In addition, abnormal levels of 3-Hydroxyphenylacetic acid are closely related to certain diseases, such as autism spectrum disorders.

Product Specifications

UNSPSC

12352005

Target

Aldehyde Dehydrogenase (ALDH) ; Apoptosis; Endogenous Metabolite; Ferroptosis; Glutathione Peroxidase; Isotope-Labeled Compounds; Keap1-Nrf2; Reactive Oxygen Species (ROS)

Related Pathways

Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Cancer; Metabolic Disease; Inflammation/Immunology; Neurological Disease; Cardiovascular Disease

Smiles

O=C(O)C([2H])(C1=C([2H])C=C([2H])C(O)=C1[2H])[2H]

Molecular Formula

C8H3D5O3

Molecular Weight

157.18

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Isoform

GPX4

Curated Selection

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