4-O-Methyl honokiol (Standard)
4-O-Methyl honokiol is a natural neolignan isolated from Magnolia officinalis, acts as a PPARγ agonist, and inhibtis NF-κB activity, used for cancer and inflammation research.
Product Specifications
CAS Number
[68592-15-4]
UNSPSC
12352005
Target
NF-κB; PPAR
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; NF-κB; Vitamin D Related/Nuclear Receptor
Field of Research
Cancer; Inflammation/Immunology
Smiles
OC1=CC=C(CC=C)C=C1C2=CC(CC=C)=C(OC)C=C2
Molecular Formula
C19H20O2
Molecular Weight
280.36
References & Citations
[1]Lee NJ, et al. 4-O-methylhonokiol, a PPARγ agonist, inhibits prostate tumour growth: p21-mediated suppression of NF-κB activity. Br J Pharmacol. 2013 Mar;168 (5) :1133-45.|[2]Lee YJ, et al. Inhibitory effect of 4-O-methylhonokiol on lipopolysaccharide-induced neuroinflammation, amyloidogenesis and memory impairment via inhibition of nuclear factor-kappaB in vitro and in vivo models. J Neuroinflammation. 2012 Feb 19;9:35.
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Reference Standards
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