EF-5 (Standard)
EF-5 (EF5; 2-Nitroimidazole) is a hypoxia labeling agent used to identify hypoxia in cells.
Product Specifications
CAS Number
152721-37-4
UNSPSC
12352005
Target
Biochemical Assay Reagents
Related Pathways
Others
Field of Research
Cancer
Smiles
O=C(NCC(F)(F)C(F)(F)F)CN1C=CN=C1[N+]([O-])=O
Molecular Formula
C8H7F5N4O3
Molecular Weight
302.16
References & Citations
[1]Wang J, et al. The 2-nitroimidazole EF5 is a biomarker for oxidoreductases that activate the bioreductive prodrug CEN-209 under hypoxia. Clin Cancer Res. 2012 Mar 15;18 (6) :1684-95.|[2]Evans SM, et al. Identification of hypoxia in cells and tissues of epigastric 9L rat glioma using EF5 [2- (2-nitro-1H-imidazol-1-yl) -N- (2,2,3,3,3-pentafluoropropyl) acetamide]. Br J Cancer. 1995 Oct;72 (4) :875-82.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
YR0117-01 5 mg
Human CD33 Monoclonal Antibody, Endotoxin 0.05 EU/mg
Sign In for Pricing
View Details YR0117-02 20 mg
Human CD33 Monoclonal Antibody, Endotoxin 0.05 EU/mg
Sign In for Pricing
View Details MBS7250461-01 48 Well
Human 6 phosphofructo 2 kinase/fructose 2, 6 biphosphatase 2 (PFKFB2) ELISA Kit
Sign In for Pricing
View Details