Seletalisib
Seletalisib (UCB5857) is potent and selective PI3Kδ inhibitor with an IC50 of 12 nM.
Product Specifications
CAS Number
1362850-20-1
Product Name Alternative
UCB5857
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
PI3K
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/Seletalisib.html
Purity
99.79
Solubility
DMSO : ≥ 83.3 mg/mL
Smiles
FC(F)(F)[C@H](NC1=C2C(C=CC=N2)=NC=N1)C3=CC4=CC=CC(Cl)=C4N=C3C5=CC=C[N+]([O-])=C5
Molecular Formula
C23H14ClF3N6O
Molecular Weight
482.85
Precautions
H302, H315, H319, H335
References & Citations
[1]Allen RA, et al. Seletalisib: Characterization of a Novel, Potent, and Selective Inhibitor of PI3Kδ. J Pharmacol Exp Ther. 2017 Apr 25. pii: jpet.116.237347.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
PI3Kδ
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
E0775Hu-01 48 Well
Human cytosolic phospholipase A2, cPLA2 ELISA KIT
Sign In for Pricing
View Details E0775Hu-02 96 Well
Human cytosolic phospholipase A2, cPLA2 ELISA KIT
Sign In for Pricing
View Details E0775Hu-03 5x 96 Tests
Human cytosolic phospholipase A2, cPLA2 ELISA KIT
Sign In for Pricing
View Details E0775Hu-04 10x 96 Tests
Human cytosolic phospholipase A2, cPLA2 ELISA KIT
Sign In for Pricing
View Details 
16423121 3x 1.0µg DNA
CMPK1 CRISPRa sgRNA lentivector (set of three targets)(Human)
Sign In for Pricing
View Details