Nogapendekin alfa (his tag)
Nogapendekin alfa (his tag), a soluble protein subunit of a human interleukin (IL) -15 variant, is a superagonist of IL-15. Nogapendekin alfa (his tag) promotes the proliferation and viability of immune cells. Nogapendekin alfa (his tag) combines with Inbakicept at a ratio of 2:1, to form N-803 (Nogapendekin alfa inbakicept), an IL-15 cytokine antibody fusion protein. N-803 reduces tumor burden by activation of NK cells and CD8+ T cells[1].
Product Specifications
CAS Number
1622189-43-8
Product Name Alternative
IL-15N72D
UNSPSC
12352203
Target
Interleukin Related
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Purity
98.62
Solubility
10 mM in DMSO
Smiles
[Nogapendekinalfa(histag)]
Molecular Weight
(13.91 kDa)
References & Citations
[1]Chen W, et al. ALT-803 in the treatment of non-muscle-invasive bladder cancer: Preclinical and clinical evidence and translational potential. Front Immunol. 2022 Nov 10;13:1040669.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
No Development Reported
Isoform
IL-15
Available Sizes
Frequently Asked Questions
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