Indusatumab vedotin
Indusatumab vedotin (MLN-0264; AKT-264) is an antibody-drug conjugate (ADC) consisting of the human anti-guanylate cyclase C (GCC) antibody linked to a microtubule-disruptor Monomethyl auristatin (HY-15162) . Indusatumab vedotin has anti-proliferative effects on pancreas cancer cell lines. Indusatumab vedotin arrests cell cycle at G2/M phase, and induces apoptosis[1].
Product Specifications
Product Name Alternative
MLN0264; TAK-264
UNSPSC
12352203
Target
Antibody-Drug Conjugates (ADCs) ; Apoptosis; Guanylate Cyclase
Related Pathways
Antibody-drug Conjugate/ADC Related; Apoptosis; GPCR/G Protein
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
96.37
Solubility
10 mM in DMSO
Smiles
[Indusatumabvedotin]
References & Citations
Shipping Conditions
Dry Ice
Storage Conditions
-80°C, protect from light
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P99662/Indusatumab-vedotin-SDS-MedChemExpress.pdf
Scientific Category
ADC Related
Clinical Information
Phase 2
CAS Number
[1514889-12-3]
Available Sizes
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