LY4101174 Antibody

LY4101174 Antibody is an ADC antibody. LY4101174 is an antibody-drug conjugate (ADC) that targets the nectin-4 protein present on the surface of certain cancer cells. It can directly deliver a potent chemotherapy agent (Exatecan (HY-13631) ) to the tumor site and is used for the study of advanced cancers, such as urothelial carcinoma, triple-negative breast cancer, and non-small cell lung cancer[1].

Product Specifications

Product Name Alternative

14A5.2 Antibody; ETx-22 Antibody

UNSPSC

12352005

Target

ADC Antibody

Related Pathways

Antibody-drug Conjugate/ADC Related

Field of Research

Cancer

Smiles

[LY4101174Antibody]

References & Citations

[1]Rosenberg J, et al. Abstract CT084: A phase 1 study of LY4101174 (ETx-22), an antibody-drug conjugate targeting nectin-4, in patients with advanced or metastatic urothelial cancer and other solid tumors (trial in progress) . Cancer Research. 2024 Apr 5;84 (7_Supplement) :CT084-.