Anti-HCMV gB Antibody (SM5-1)

Anti-HCMV gB Antibody (SM5-1) is an efficient neutralizing human monoclonal antibody that targets the human cytomegalovirus (HCMV) glycoprotein B (gB) . Anti-HCMV gB Antibody (SM5-1) neutralizes HCMV by blocking the conformational changes of gB and interfering with its binding to the gH/gL complex. Anti-HCMV gB Antibody (SM5-1) can broadly neutralize different virus strains and inhibit the infection of various cell types (such as fibroblasts, epithelial cells, and dendritic cells) . Anti-HCMV gB Antibody (SM5-1) can be used in HCMV vaccine research[1].

Product Specifications

UNSPSC

12352005

Target

CMV

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

[Anti-HCMVgBAntibody(SM5-1)]

References & Citations

[1]Spindler N, et al. Structural basis for the recognition of human cytomegalovirus glycoprotein B by a neutralizing human antibody. PLoS Pathog. 2014 Oct 9;10 (10) :e1004377.