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MEN1112

MEN1112 (OBT357NF) is a selective humanized monoclonal antibody targeting the Bst1/CD157 antigen (EC50=1 nM) . MEN1112 exerts potent antitumor activity against acute myeloid leukemia (AML) cells. MEN1112 is promising for research of hematological malignancies such as AML[1].

Product Specifications

Product Name Alternative

OBT357NF; OBT357

UNSPSC

12352100

Target

Transmembrane Glycoprotein

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

References & Citations

[1]Aud D, et al. MEN1112, a novel humanized de-fucosylated monoclonal antibody with high affinity and specificity for Bst1/CD157 antigen and enhanced CD16 binding[J]. Blood, 2014, 124 (21) : 3607.

Shipping Conditions

Room temperature

Scientific Category

Inhibitory Antibodies

Clinical Information

No Development Reported

Frequently Asked Questions

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