MEN1112
MEN1112 (OBT357NF) is a selective humanized monoclonal antibody targeting the Bst1/CD157 antigen (EC50=1 nM) . MEN1112 exerts potent antitumor activity against acute myeloid leukemia (AML) cells. MEN1112 is promising for research of hematological malignancies such as AML[1].
Product Specifications
Product Name Alternative
OBT357NF; OBT357
UNSPSC
12352100
Target
Transmembrane Glycoprotein
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
References & Citations
[1]Aud D, et al. MEN1112, a novel humanized de-fucosylated monoclonal antibody with high affinity and specificity for Bst1/CD157 antigen and enhanced CD16 binding[J]. Blood, 2014, 124 (21) : 3607.
Shipping Conditions
Room temperature
Scientific Category
Inhibitory Antibodies
Clinical Information
No Development Reported
Curated Selection
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