AGS-009
AGS-009 is a humanized monoclonal neutralising antibody targeting IFN-α. AGS-009 significantly reduces activated lymphocytes, such as CD4+ and CD8+ T cells as well as B cells in SIV infection rhesus macaque models. AGS-009 can be used for autoimmune diseases like systemic lupus erythematosus (SLE) and HIV infections research[1][2].
Product Specifications
UNSPSC
12352100
Target
HIV; IFNAR
Related Pathways
Anti-infection; Immunology/Inflammation
Field of Research
Infection; Inflammation/Immunology
References & Citations
[1]Mathian A, et al. Targeting interferons in systemic lupus erythematosus: current and future prospects. Drugs. 2015 May;75 (8) :835-46.|[2]Carnathan D, et al. Reduced Chronic Lymphocyte Activation following Interferon Alpha Blockade during the Acute Phase of Simian Immunodeficiency Virus Infection in Rhesus Macaques. J Virol. 2018 Apr 13;92 (9) :e01760-17.
Shipping Conditions
Room temperature
Scientific Category
Inhibitory Antibodies
Clinical Information
No Development Reported
Frequently Asked Questions
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