ING-1
ING-1 (heMab) is a high-affinity humanized monoclonal antibody against epithelial cell adhesion molecule (Ep-CAM) . ING-1 is a transmembrane glycoprotein mediating Ca2+. ING-1 binds to Ep-CAM on tumor cells and exhibits potent in vitro activity, targeting and inhibiting tumor growth and metastasis in mouse cancer models. ING-1 is useful in the research of breast, colorectal, and lung cancers, among other cancers[1][2].
Product Specifications
Product Name Alternative
HeMab
UNSPSC
12352100
Target
Transmembrane Glycoprotein
Related Pathways
Immunology/Inflammation
Field of Research
Cancer
References & Citations
[1]Ammons WS, et al. In vitro and in vivo pharmacology and pharmacokinetics of a human engineered monoclonal antibody to epithelial cell adhesion molecule. Neoplasia. 2003 Mar-Apr;5 (2) :146-54.|[2]Ruan HH, et al. ING-1 (heMAb), a monoclonal antibody to epithelial cell adhesion molecule, inhibits tumor metastases in a murine cancer model. Neoplasia. 2003 Nov-Dec;5 (6) :489-94.
Shipping Conditions
Room temperature
Scientific Category
Inhibitory Antibodies
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
GTR15379577 1 Vial
Lentiviral human STEAP2 sgRNA gene knockout kit - Lentiviral human STEAP2 sgRNA gene knockout kit (plasmid)
Sign In for Pricing
View Details 
ARP47665_P050-FITC 100 µL
HOMEZ Antibody - middle region : FITC (ARP47665_P050-FITC)
Sign In for Pricing
View Details 131036-ML750 100 µL
PDCD6 (ALG2, Programmed Cell Death Protein 6, Apoptosis-linked Gene 2 Protein, Probable Calcium-binding Protein ALG-2) (MaxLight 750) discontinued
Sign In for Pricing
View Details