AK006
AK006 is a humanized IgG1 monoclonal antibody agonist targeting Sialic acid-binding immunoglobulin-like lectin6 (Siglec-6) . AK006 potently inhibits IgE-mediated human mast cell activation. AK006 can be used for inflammatory diseases like chronic urticaria (CU) and asthma research[1][2].
Product Specifications
UNSPSC
12352100
Target
Others
Related Pathways
Others
Field of Research
Inflammation/Immunology
References & Citations
[1]Poto R, et al. Human Lung Mast Cells: Therapeutic Implications in Asthma. Int J Mol Sci. 2022 Nov 21;23 (22) :14466. |[2]Metz M, et al. Mast cell silencing: A novel therapeutic approach for urticaria and other mast cell-mediated diseases. Allergy. 2024 Jan;79 (1) :37-51.
Shipping Conditions
Room temperature
Scientific Category
Inhibitory Antibodies
Clinical Information
No Development Reported
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