HLX-22
HLX-22 is a humanized monoclonal antibody targeting HER2. HLX-22 induces apoptosis in HER2-overexpressing breast and gastric cancer cells combined with Trastuzumab (HY-P9907) . HLX-22 has potent antitumor activity against advanced solid tumors[1].
Product Specifications
CAS Number
[2851060-90-5]
Product Name Alternative
AC101
UNSPSC
12352203
Target
EGFR
Related Pathways
JAK/STAT Signaling; Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Purity
99.47
References & Citations
[1]Zhu X, et al. HLX22, an anti-HER-2 monoclonal antibody, in patients with advanced solid tumors overexpressing human epidermal growth factor receptor 2: an open-label, dose-escalation, phase 1 trial[J]. Investigational New Drugs, 2023, 41 (3) : 473-482.
Shipping Conditions
Dry Ice
Storage Conditions
-80°C
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P991588/HLX-22-SDS-MedChemExpress.pdf
Scientific Category
Inhibitory Antibodies
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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