MEDI-5884
MEDI-5884 is a humanized IgG4Pκ neutralizing monoclonal antibody targeting Endothelial lipase (EL) . MEDI-5884 inhibits EL and increases quantity (particularly phosphatidylinositols and cholesteryl esters) and function of high-density lipoproteins (HDL) . MEDI-5884 can be used for cardiovascular disease like coronary artery disease (CAD) research[1].
Product Specifications
CAS Number
2643310-75-0
Product Name Alternative
REG-101
UNSPSC
12352203
Target
ATGL
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
References & Citations
[1]Rosenbaum A I, et al. Inhibition of endothelial lipase by MEDI5884 normalizes phosphatidylinositol levels in coronary artery disease patients[J]. bioRxiv, 2024: 2024.05. 30.596497.
Shipping Conditions
Room temperature
Scientific Category
Inhibitory Antibodies
Clinical Information
No Development Reported
Frequently Asked Questions
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