ALD1910
ALD1910 is a humanized monoclonal antibody against PACAP38 and PACAP27. ALD1910 blocks PACAP signaling through the pituitary adenylate cyclase-activating peptide type I receptor (PAC1-R), vasoactive intestinal peptide receptor 1 (VPAC1-R), and VPAC2-R. ALD1910 recognizes a nonlinear epitope within PACAP and blocks its binding to the cell surface. ALD1910 can be used for the study of PACAP-mediated migraine[1].
Product Specifications
UNSPSC
12352203
Target
PACAP Receptor
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Purity
96.85
References & Citations
[1]Cristina Moldovan Loomis, et al. Pharmacologic Characterization of ALD1910, a Potent Humanized Monoclonal Antibody against the Pituitary Adenylate Cyclase-Activating Peptide. J Pharmacol Exp Ther. 2019 Apr;369 (1) :26-36.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
abx537829 96 Tests
Mouse Presenilins-associated rhomboid-like protein, mitochondrial (PARL) ELISA Kit
Sign In for Pricing
View Details 
GTR10403520 96 Well
Guinea Pig Olfactory receptor 10A6 (OR10A6) ELISA kit
Sign In for Pricing
View Details 