Anti-STEAP2 Antibody
Anti-STEAP2 Antibody (AZD0516 antibody) is a selective six-transmembrane epithelial antigen of prostate 2 (STEAP2) inhibitor. Anti-STEAP2 Antibody inhibits the proliferation, migration and invasion of prostate cancer cells by blocking the STEAP2-mediated ERK/MAPK signaling pathway. Anti-STEAP2 Antibody is promising for research of prostate cancer[1][2].
Product Specifications
Product Name Alternative
AZD0516 antibody
UNSPSC
12352203
Target
ERK; p38 MAPK
Related Pathways
MAPK/ERK Pathway; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Purity
99.65
Smiles
[Anti-STEAP2Antibody]
Molecular Weight
(147.34 kDa)
References & Citations
[1]Jones LA, et al. Investigating STEAP2 as a potential therapeutic target for the treatment of aggressive prostate cancer. Cell Mol Biol (Noisy-le-grand) . 2023 Apr 30;69 (4) :179-187.|[2]Zanvit P, et al. Antitumor activity of AZD0754, a dnTGFβRII-armored, STEAP2-targeted CAR-T cell therapy, in prostate cancer. J Clin Invest. 2023 Nov 15;133 (22) :e169655.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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