MG-1131
MG-1131 is a human monoclonal antibody (mAb) targeting TIGIT. MG-1131 activates NF-κB signaling in T cells and enhances NK-mediated tumor killing activity in a PVR-dependent manner. MG-1131 blocks TIGIT to increase IFN-γ secretion. MG-1131 can be used in anti-tumor immunity research. Recommended isotype control: Human IgG1 kappa, Isotype Control (HY-P99001) [1].
Product Specifications
UNSPSC
12352203
Target
IFNAR; NF-κB; Transmembrane Glycoprotein
Related Pathways
Immunology/Inflammation; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
[MG-1131]
References & Citations
[1]Lee J, et al. Unveiling the Impact of BMP9 in Liver Diseases: Insights into Pathogenesis and Therapeutic Potential. Biomolecules. 2024 Aug 15;14 (8) :1013.
Shipping Conditions
Room temperature
Scientific Category
Inhibitory Antibodies
Clinical Information
No Development Reported
Curated Selection
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