MB-314
MB-314 is a human IgG1 monoclonal antibody (mAb) targeting Lewis Y. MB-314 induces enhanced antibody-dependent cell-mediated cytotoxicity (ADCC) activity. MB-314 increases the release of IFN-γ, TNF-α, MCP-1, and IL-6. MB-314 can be used in cancer research[1].
Product Specifications
UNSPSC
12352203
Target
IFNAR; TNF Receptor; Transmembrane Glycoprotein
Related Pathways
Apoptosis; Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
[MB-314]
References & Citations
[1]Kircheis R, et al. Correlation of ADCC activity with cytokine release induced by the stably expressed, glyco-engineered humanized Lewis Y-specific monoclonal antibody MB314. MAbs. 2012 Jul-Aug;4 (4) :532-41.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P991426/
Scientific Category
Inhibitory Antibodies
Clinical Information
No Development Reported
Curated Selection
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