GSK1995057
GSK1995057 is a human monoclonal antibody (mAb) targeting TNFRSF1A. GSK1995057 attenuates pulmonary neutrophilia, inflammatory cytokine release and signs of endothelial injury in bronchoalveolar lavage and serum samples. GSK1995057 can be used in Acute lung injury and Adult respiratory distress syndrome research. Recommended isotype control: dAb (VHH-His) [1].
Product Specifications
UNSPSC
12352203
Target
TNF Receptor
Related Pathways
Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Smiles
[GSK1995057]
References & Citations
[1]Proudfoot A, et al. Novel anti-tumour necrosis factor receptor-1 (TNFR1) domain antibody prevents pulmonary inflammation in experimental acute lung injury. Thorax. 2018 Aug;73 (8) :723-730.
Shipping Conditions
Room temperature
Scientific Category
Inhibitory Antibodies
Clinical Information
No Development Reported
Isoform
TNFRSF1A/CD120a
Curated Selection
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