ASP8374
ASP8374 is a human IgG4 monoclonal antibody (mAb) targeting TIGIT. ASP8374 increases IL-2 production in Jurkat cells and IFN-γ and TNF-α production in human PBMCs. ASP8374 can be used in advanced solid tumors research. Recommended isotype control: Human IgG4 kappa, Isotype Control (HY-P99003) [1].
Product Specifications
UNSPSC
12352203
Target
IFNAR; TNF Receptor; Transmembrane Glycoprotein
Related Pathways
Apoptosis; Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
[ASP8374]
References & Citations
[1]Shirasuna K, et al. Characterization of ASP8374, a fully-human, antagonistic anti-TIGIT monoclonal antibody. Cancer Treat Res Commun. 2021;28:100433.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P991393/
Scientific Category
Inhibitory Antibodies
Clinical Information
No Development Reported
Curated Selection
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