JST-TfR09
TXB4 (PPMX-T003) is a human monoclonal antibody (mAb) targeting CD71. JST-TfR09 can induce ferroptosis by reducing ferritin levels in ATLL cell lines, increasing the generation of ferrous iron and reactive oxygen species (ROS), and inducing lipid peroxidation via malondialdehyde. JST-TfR09 can be used in leukemia research. Recommended isotype control: Human IgG1 kappa, Isotype Control (HY-P99001) [1].
Product Specifications
Product Name Alternative
PPMX-T003
UNSPSC
12352203
Target
Ferroptosis; Reactive Oxygen Species (ROS) ; Transferrin Receptor
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
[JST-TfR09]
References & Citations
[1]Fauzi YR, et al. Anti-transferrin receptor antibody (JST-TFR09/PPMX-T003) induces ferroptosis in adult T-cell leukemia/lymphoma (ATLL) cells. Biochem Biophys Res Commun. 2025 Apr 5;756:151564.
Shipping Conditions
Room temperature
Scientific Category
Inhibitory Antibodies
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
RARa/Ig/PO 1 mL
Rabbit anti Rat IgG1 IgG2a IgG2b IgG2c IgA IgM (heavy and light chains), conjugated with Horseradish peroxidase
Ask
View Details 51149124 3x 1.0µg DNA
Zfp825 CRISPRa sgRNA lentivector (set of three targets)(Mouse)
Ask
View Details 