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APNmAb005

APNmAb005 is a human monoclonal antibody (mAb) targeting MAPT/Tau/PHF-tau. APNmAb005 blocks tau seeding in vitro and rescues neuronal loss in rTG4510 mice. APNmAb005 can be used in Alzheimer’s disease (AD) research[1].

Product Specifications

UNSPSC

12352203

Hazard Statement

H302, H315, H319, H335

Target

Tau Protein

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Purity

97.64

Smiles

[APNmAb005]

Molecular Weight

(145.92 kDa)

Precautions

H302, H315, H319, H335

References & Citations

[1]Tai C Y, et al. APNmAb005, an anti‐tau antibody targeting synaptic tau oligomers, in Phase 1 for treatment of Alzheimer’s Disease and primary tauopathies[J]. Alzheimer's & Dementia, 2023, 19: e076888.

Shipping Conditions

Dry Ice

Storage Conditions

-80°C

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-P991373/APNmAb005-SDS-MedChemExpress.pdf

Scientific Category

Inhibitory Antibodies

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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