SBT-100
SBT-100 is a human monoclonal antibody (mAb) targeting STAT3. SBT-100 inhibits IL-6-mediated P-STAT3 nuclear translocation in HEp-2 and PANC-1 cells. SBT-100 has tumor growth inhibitory effects on MDA-MB-231[1].
Product Specifications
UNSPSC
12352203
Target
STAT
Related Pathways
JAK/STAT Signaling; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Smiles
[SBT-100]
References & Citations
[1]Singh S, et al. Novel single-domain antibody (sdAb), SBT-100, localizes in the cytoplasm to inhibit IL-6 mediated P-STAT3 nuclear translocation in cancer cells[J]. Cancer Research, 2018, 78 (13_Supplement) : 5436-5436.
Shipping Conditions
Room temperature
Scientific Category
Inhibitory Antibodies
Clinical Information
No Development Reported
Frequently Asked Questions
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