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AR20.5

AR20.5 is a human monoclonal antibody (mAb) targeting MUC1. AR20.5 increases the number of activated CD8 T cells, CD3+CD4−CD8− (DN) T cells, and mature dendritic cells in pancreatic tumor-bearing mice. AR20.5 can be used in anti-pancreatic cancer immunity research[1].

Product Specifications

UNSPSC

12352203

Target

Mucin

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

[AR20.5]

References & Citations

[1]Mehla K, et al. Combination of mAb-AR20.5, anti-PD-L1 and PolyICLC inhibits tumor progression and prolongs survival of MUC1.Tg mice challenged with pancreatic tumors. Cancer Immunol Immunother. 2018 Mar;67 (3) :445-457.

Shipping Conditions

Room temperature

Scientific Category

Inhibitory Antibodies

Clinical Information

No Development Reported

Frequently Asked Questions

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