CID-663143

CID-663143 targets microtubule-associated proteins, not tubulin itself, to inhibit the polymerization process within cells. CID-663143 inhibits cancer cell growth (IC50: [1].

Product Specifications

CAS Number

[578723-96-3]

UNSPSC

12352005

Target

Microtubule/Tubulin

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Cytoskeleton

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/cid-663143.html

Solubility

10 mM in DMSO

Smiles

COC1=C(C=CC=C1)C2=NN=C3SCC(C4=CC=C(OCC)C=C4)=NN23

Molecular Formula

C19H18N4O2S

Molecular Weight

366.44

References & Citations

[1]Yang WS, et al. Identification of Simple Compounds with Microtubule-Binding Activity That Inhibit Cancer Cell Growth with High Potency. ACS Med Chem Lett. 2012 Jan 12;3 (1) :35-38.