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IRAB-B

IRAB-B is a human monoclonal antibody targeting INSR. IRAB-B is an insulin receptor (IR) antagonist and can be used in the study of insulin resistance and diabetes[1].

Product Specifications

UNSPSC

12352203

Target

Insulin Receptor

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology; Metabolic Disease; Inflammation/Immunology

Purity

98.30

Smiles

I[R][*][B][B]

Molecular Weight

(145.21 kDa)

References & Citations

[1]Cieniewicz AM, et al. Novel Monoclonal Antibody Is an Allosteric Insulin Receptor Antagonist That Induces Insulin Resistance. Diabetes. 2017 Jan;66 (1) :206-217.

Shipping Conditions

Dry Ice

Storage Conditions

-80°C

Scientific Category

Inhibitory Antibodies

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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