MK-1966
MK-1966 is a humanized monoclonal antibody inhibitor targeting interleukin-10 (IL-10) . MK-1966 blocks the inhibitory effects of IL-10 on immune cells such as macrophages and dendritic cells to restore anti-tumor immune responses. MK-1966 is promising for research of cancers[1].
Product Specifications
UNSPSC
12352203
Hazard Statement
H302, H315, H319, H335
Target
Interleukin Related
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Purity
96.17
Smiles
[MK-1966]
Precautions
H302, H315, H319, H335
References & Citations
[1]Phan U, et al. Development of the anti-IL-10 mAb MK-1966 in combination with in situ vaccination of a TLR9 agonist SD-101 for cancer immunotherapy[J]. European Journal of Cancer, 2016, 69: S91-S92.
Shipping Conditions
Dry Ice
Storage Conditions
-80°C
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 1
Isoform
IL-10
Available Sizes
Curated Selection
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