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BAT1006

BAT1006 is a monoclonal antibody targeting HER2 extracellular domain II with enhanced antibody-dependent cell-mediated cytotoxicity (ADCC) for the study of HER2-positive locally advanced/metastatic solid tumors. BAT1006 has an approximately 5-fold enhanced ADCC effect compared to pertuzumab and exhibits potent anti-tumor activity in the HER2-positive Calu-3 xenograft mouse model[1].

Product Specifications

UNSPSC

12352203

Target

EGFR

Related Pathways

JAK/STAT Signaling; Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Smiles

[BAT1006]

References & Citations

[1]Xingxing Mei, et al. Abstract CT189: A phase I study of BAT1006, a novel anti-HER2 antibody, in patients with locally advanced/metastatic solid tumors. Cancer research. Cancer Res (2023) 83 (8_Supplement) : CT189.

Shipping Conditions

Room temperature

Scientific Category

Inhibitory Antibodies

Clinical Information

Phase 2

Frequently Asked Questions

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