MK-4830
MK-4830 is a fully humanized monoclonal antibody of the immunoglobulin G4 subclass that specifically binds to ILT4 and blocks its interaction with HLA-G and other ligands. MK-4830 inhibits tumor growth in humanized mouse cancer models[1].
Product Specifications
UNSPSC
12352203
Target
Others
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
[MK-4830]
References & Citations
[1]Lillian L Siu, et al. First-in-Class Anti-immunoglobulin-like Transcript 4 Myeloid-Specific Antibody MK-4830 Abrogates a PD-1 Resistance Mechanism in Patients with Advanced Solid Tumors. Clin Cancer Res. 2022 Jan 1;28 (1) :57-70.
Shipping Conditions
Room temperature
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 2
Curated Selection
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