RG7287

RG7287 is an activating antibody inhibitor targeting human CDCP1. RG7287 prevents the loss of contact inhibition caused by the co-transformation of NIH3T3 cells with CDCP1 and Src in focus formation assays. RG7287 inhibits tumor cell proliferation and leads to a significant reduction in CDCP1 levels[1].

Product Specifications

UNSPSC

12352203

Hazard Statement

H302, H315, H319, H335

Target

Others

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Purity

97.666

Smiles

[RG7287]

Precautions

H302, H315, H319, H335

References & Citations

[1]Gwendlyn Kollmorgen, et al. Antibody mediated CDCP1 degradation as mode of action for cancer targeted therapy. Mol Oncol. 2013 Dec;7 (6) :1142-51.

Shipping Conditions

Dry Ice

Storage Conditions

-80°C

Scientific Category

Inhibitory Antibodies

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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