Flt-3L-Ig (hum/hum)

Flt-3L-Ig (hum/hum) (hFlt3L) is a Flt3 activator. Flt-3L-Ig (hum/hum) enhances OKT3-induced inflammatory cytokine release from myeloid and dendritic cells in BRGSF-CBC mice, as well as the number and distribution of human immune cells, exhibiting cytokine release syndrome (CRS) [1].

Product Specifications

Product Name Alternative

Human Flt3L; hFlt3L

UNSPSC

12352203

Target

FLT3

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Purity

Smiles

[Flt-3L-Ig(hum/hum)]

Molecular Weight

(86.938 kDa)

References & Citations

[1]Martin GH, et al. Myeloid and dendritic cells enhance therapeutics-induced cytokine release syndrome features in humanized BRGSF-HIS preclinical model. Front Immunol. 2024 Feb 7;15:1357716.