Flt-3L-Ig (hum/hum)
Flt-3L-Ig (hum/hum) (hFlt3L) is a Flt3 activator. Flt-3L-Ig (hum/hum) enhances OKT3-induced inflammatory cytokine release from myeloid and dendritic cells in BRGSF-CBC mice, as well as the number and distribution of human immune cells, exhibiting cytokine release syndrome (CRS) [1].
Product Specifications
Product Name Alternative
Human Flt3L; hFlt3L
UNSPSC
12352203
Target
FLT3
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Purity
98
Smiles
[Flt-3L-Ig(hum/hum)]
Molecular Weight
(86.938 kDa)
References & Citations
[1]Martin GH, et al. Myeloid and dendritic cells enhance therapeutics-induced cytokine release syndrome features in humanized BRGSF-HIS preclinical model. Front Immunol. 2024 Feb 7;15:1357716.
Shipping Conditions
Dry Ice
Storage Conditions
-80°C
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P991208/Flt-3L-Ig-hum-hum-SDS-MedChemExpress.pdf
Scientific Category
Inhibitory Antibodies
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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