OM-7D3-B3
OM-7D3-B3 is a monoclonal antibody targeting human claudin-1 (CLDN1) (Kd = 4 nM) . OM-7D3-B3 blocks the process in which CLDN1 is involved in the entry of hepatitis C virus (HCV) into cells. OM-7D3-B3 is promising for research of HCV infection[1][2].
Product Specifications
UNSPSC
12352203
Target
Claudin; HCV
Related Pathways
Anti-infection; Cytoskeleton
Applications
COVID-19-anti-virus
Field of Research
Infection
Purity
97.98
References & Citations
[1]Fofana I, et al. Monoclonal anti-claudin 1 antibodies prevent hepatitis C virus infection of primary human hepatocytes. Gastroenterology. 2010 Sep;139 (3) :953-64, 964.e1-4.|[2]Hashimoto Y, et al. Claudin-targeted drug development using anti-claudin monoclonal antibodies to treat hepatitis and cancer. Ann N Y Acad Sci. 2017 Jun;1397 (1) :5-16.
Shipping Conditions
Dry Ice
Storage Conditions
-80°C
Scientific Category
Inhibitory Antibodies
Clinical Information
No Development Reported
Isoform
CLDN1
Available Sizes
Frequently Asked Questions
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