OM-7D3-B3

OM-7D3-B3 is a monoclonal antibody targeting human claudin-1 (CLDN1) (Kd = 4 nM) . OM-7D3-B3 blocks the process in which CLDN1 is involved in the entry of hepatitis C virus (HCV) into cells. OM-7D3-B3 is promising for research of HCV infection[1][2].

Product Specifications

UNSPSC

12352203

Target

Claudin; HCV

Related Pathways

Anti-infection; Cytoskeleton

Applications

COVID-19-anti-virus

Field of Research

Infection

Purity

97.98

References & Citations

[1]Fofana I, et al. Monoclonal anti-claudin 1 antibodies prevent hepatitis C virus infection of primary human hepatocytes. Gastroenterology. 2010 Sep;139 (3) :953-64, 964.e1-4.|[2]Hashimoto Y, et al. Claudin-targeted drug development using anti-claudin monoclonal antibodies to treat hepatitis and cancer. Ann N Y Acad Sci. 2017 Jun;1397 (1) :5-16.