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AMG-119

AMG-119 is a humanized IgG1 monoclonal antibody that targets delta-like ligand 3 (DLL3) . AMG-119 can be used for the study of relapsed/refractory (R/R) small cell lung cancer (SCLC) . Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001) [1].

Product Specifications

UNSPSC

12352203

Target

Notch

Related Pathways

Neuronal Signaling; Stem Cell/Wnt

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

[AMG-119]

References & Citations

[1]Zhou D, et al. Clinical Pharmacology Profile of AMG 119, the First Chimeric Antigen Receptor T (CAR-T) Cell Therapy Targeting Delta-Like Ligand 3 (DLL3), in Patients with Relapsed/Refractory Small Cell Lung Cancer (SCLC) . J Clin Pharmacol. 2024 Mar;64 (3) :362-370.

Shipping Conditions

Room temperature

Scientific Category

Inhibitory Antibodies

Clinical Information

No Development Reported

Curated Selection

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