MGD010
MGD010 is a bispecific CD32B (FcγRIIb) and CD79B antibody. MGD010 inhibits activated B-cells by delivering a negative signal via simultaneous co-ligation of CD32B (FcγRIIb), with the BCR component, CD79B. MGD010 has the potential for the study of autoimmune disorders[1].
Product Specifications
Product Name Alternative
PRV-3279
UNSPSC
12352203
Target
Fc Receptor (FcR)
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
References & Citations
[1]Pandya, N., et al. OP0201 Safety, Tolerability, and Functional Activity of MGD010, A Dart® Molecule Targeting CD32B and CD79B, Following A Single Dose Administration in Healthy Volunteers. Annals of the Rheumatic Diseases, 2016. 75 (Suppl 2), 132.3-133.
Shipping Conditions
Room temperature
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 2
Curated Selection
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