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TQB-2858

TQB-2858 is a bifunctional fusion protein composed of a monoclonal antibody against PD-L1 fused with the extracellular domain of TGF-β receptor. TQB-2858 has a high affinity for PD-L1, TGF-β1, and TGF-β3 and exhibited high PD-L1 target occupancy. TQB-2858 can be used for the study of osteosarcoma and alveolar soft part sarcoma (ASPS) [1].

Product Specifications

UNSPSC

12352203

Target

PD-1/PD-L1

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

References & Citations

[1]Xie L, et al. Exploratory study of an anti-PD-L1/TGF-β antibody, TQB2858, in patients with refractory or recurrent osteosarcoma and alveolar soft part sarcoma: a report from Chinese sarcoma study group (TQB2858-Ib-02) . BMC Cancer. 2023 Sep 15;23 (1) :868.

Shipping Conditions

Room temperature

Scientific Category

Inhibitory Antibodies

Clinical Information

Phase 2

Frequently Asked Questions

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