ARGX-119

ARGX-119 is a first-in-class humanized agonist monoclonal antibody specific for muscle-specific kinase (MuSK) . ARGX-119 can be used for the study of neuromuscular diseases. The isotype control for ARGX-119 can refer to Human IgG1 lambda1, Isotype Control (HY-P99992) [1].

Product Specifications

CAS Number

[2966023-63-0]

UNSPSC

12352203

Target

NAChR

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Purity

99.739

Smiles

[ARGX-119]

Molecular Weight

(143.83 kDa)

References & Citations

[1]Vanhauwaert R, et al. ARGX-119 is an agonist antibody for human MuSK that reverses disease relapse in a mouse model of congenital myasthenic syndrome. Sci Transl Med. 2024 Sep 18;16 (765) :eado7189.