ARGX-119
ARGX-119 is a first-in-class humanized agonist monoclonal antibody specific for muscle-specific kinase (MuSK) . ARGX-119 can be used for the study of neuromuscular diseases. The isotype control for ARGX-119 can refer to Human IgG1 lambda1, Isotype Control (HY-P99992) [1].
Product Specifications
CAS Number
[2966023-63-0]
UNSPSC
12352203
Target
NAChR
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Purity
99.739
Smiles
[ARGX-119]
Molecular Weight
(143.83 kDa)
References & Citations
[1]Vanhauwaert R, et al. ARGX-119 is an agonist antibody for human MuSK that reverses disease relapse in a mouse model of congenital myasthenic syndrome. Sci Transl Med. 2024 Sep 18;16 (765) :eado7189.
Shipping Conditions
Dry Ice
Storage Conditions
-80°C
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P991066/ARGX-119-SDS-MedChemExpress.pdf
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 2
Available Sizes
Curated Selection
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