Forimtamig
Forimtamig (RG-6324) is a GPRC5DxCD3 T-cell-engaging bispecific antibody. Forimtamig has a 2 + 1 format, comprising two high-affinity GPRC5D binding moieties and one CD3 binder. Forimtamig further features a P329G LALA mutated Fc domain that inhibits Fcγ receptor and C1q binding, yet retains binding to the neonatal Fc receptor. The isotype control for Forimtamig can refer to Human IgG1 kappa, Isotype Control.
Product Specifications
CAS Number
2649379-96-2
Product Name Alternative
RG-6234; RO-7425781
UNSPSC
12352203
Target
CD3
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Purity
99.96
Smiles
[Forimtamig]
Molecular Weight
(169.38 kDa)
References & Citations
[1]O'Brien N, et al. T cell margination: investigating the detour of T cells following forimtamig treatment in humanized mice. MAbs. 2025 Dec;17 (1) :2440578.
Shipping Conditions
Dry Ice
Storage Conditions
-80°C
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 2
Available Sizes
Frequently Asked Questions
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