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Atrosimab

Atrosimab (ATM-001) is a Fv-Fc1κ fusion protein with strong binding to human TNFR1 with an EC50 value of 0.37 nM. Atrosimab potently inhibits TNF-induced activation of TNFR1. Atrosimab has the potential for the study of chronic inflammatory diseases[1].

Product Specifications

Product Name Alternative

ATM-001

UNSPSC

12352203

Target

TNF Receptor

Related Pathways

Apoptosis

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Purity

99

Smiles

[Atrosimab]

Molecular Weight

(72.338 kDa)

References & Citations

[1]Richter F, et al. Improved monovalent TNF receptor 1-selective inhibitor with novel heterodimerizing Fc. MAbs. 2019 May/Jun;11 (4) :653-665.

Shipping Conditions

Dry Ice

Storage Conditions

-80°C

Scientific Category

Inhibitory Antibodies

Clinical Information

Phase 1

Available Sizes

Frequently Asked Questions

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