CD300e, Mouse (HEK293, hFc)
CD300e Protein is an immune activating receptor expressed by myeloid cells, suggesting its involvement in cellular signaling and immune responses. Engagement of CD300e provides survival signals to cells, triggering the expression of activation markers and the release of pro-inflammatory cytokines. The ligation of CD300e in monocytes blocks the expression of the human leukocyte antigen (HLA) class II, affecting its synthesis. In addition, CD300e recognizes sphingomyelin and thereby regulates nonclassical and intermediate monocyte functions through FcRγ and DAP12. CD300e Protein, Mouse (CHO, mFc) is the recombinant mouse-derived CD300e/LMIR6 protein, expressed by CHO , with C-mFc labeled tag.
Product Specifications
Product Name Alternative
CD300e Protein, Mouse (HEK293, hFc), Mouse, HEK293
UNSPSC
12352202
Molecular Formula
217306 (Gene_ID) Q8K249/NP_742047.1 (L18-S154) (Accession)
Molecular Weight
Approximately 49.8 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
Shipping Conditions
Room temperature in continental US; may vary elsewhere.
Scientific Category
Recombinant Proteins
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