FOLR1, Mouse (Biotinylated, HEK293, His-Avi)

FOLR1 Protein, binding to folate and reduced folic acid derivatives, facilitates their delivery into cells. It maintains high affinity under neutral pH but undergoes a conformational change upon endocytosis, reducing affinity and releasing folates in slightly acidic pH. Crucial for embryonic development, cell proliferation, and renal folate reabsorption. FOLR1 Protein, Mouse (Biotinylated, HEK293, His-Avi) is the recombinant mouse-derived FOLR1 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of FOLR1 Protein, Mouse (Biotinylated, HEK293, His-Avi) is 208 a.a., with molecular weight of 32-45 kDa.