FOLR2, Human (Biotinylated, HEK293, His-Avi)

FOLR2 Protein binds folate, enabling the transport of 5-methyltetrahydrofolate into cells with high affinity under neutral pH. Upon endocytosis, exposure to slightly acidic pH induces a conformational change, substantially reducing FOLR2's folate affinity and releasing it from the receptor. FOLR2 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived FOLR2 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of FOLR2 Protein, Human (Biotinylated, HEK293, His-Avi) is 212 a.a., with molecular weight of 30-40 kDa.