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IL-12R beta 1, Human (Biotinylated, HEK293, Fc-Avi)

Selected Variant

HY-P78862-01

Size: 25 µg

IL-12R beta 1 protein is an IL-12 cytokine surface receptor that activates the Jak-Stat signaling cascade pathway and is involved in IL-12-mediated immune regulation. IL-12R beta 1 Protein, Human (Biotinylated, HEK293, Fc-Avi) is a biotinylated protein expressed by HEK293 cells with a C-terminal Avi and hFc tag[1].

Product Specifications

Product Name Alternative

IL-12R beta 1 Protein, Human (Biotinylated, HEK293, Fc-Avi), Human, HEK293

UNSPSC

12352202

Molecular Formula

3594 (Gene_ID) P42701-1 (C24-E540) (Accession)

Molecular Weight

Approximately 110 kDa

References & Citations

[1]C E Verhagen, et al. Residual type 1 immunity in patients genetically deficient for interleukin 12 receptor beta1 (IL-12Rbeta1) : evidence for an IL-12Rbeta1-independent pathway of IL-12 responsiveness in human T cells. J Exp Med. 2000 Aug 21;192 (4) :517-28.|[2]Esther van de Vosse, et al. IL-12Rβ1 deficiency: mutation update and description of the IL12RB1 variation database. Hum Mutat. 2013 Oct;34 (10) :1329-39.|[3]H Nagayama, et al. IL-12 responsiveness and expression of IL-12 receptor in human peripheral blood monocyte-derived dendritic cells. J Immunol. 2000 Jul 1;165 (1) :59-66.

Shipping Conditions

Room temperature in continental US; may vary elsewhere.

Scientific Category

Recombinant Proteins

Available Sizes

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